Transcriptome analysis of osteoporosis in DN patients treated with traditional Chinese medicine showed that miR-574 may play an important role in DN-related osteoporosis, with the therapeutic effects of kaempferol and quercetin on Leri–Weill dyschondrosteosis in DN-related osteoporosis potentially mediated by miR-574 by targeting MAPK1 (43). The gene discussed is MAPK1; the disease is Leri-Weill dyschondrosteosis.