As shown in Figure 6B, mice that were infected with 104 IL-6 Tg-PbANKA/LISP2 SPZ (group 1) not only did not show any parasitemia after the first and the second infection with the recombinant parasites, as expected, but more interestingly did not develop any parasitemia upon challenge with WT parasites. Here, IL6 is linked to parasitic infectious disease.