13 biomarkers including β-catenin, C-MYC, GATA-4, CXCL13, DAPK1, TIMP3, DC-SIGN, EGFR, PIM2, GRIN2B, SLC5A8, VCAM-1 and CDH1 are related to the development of gastric cancer, and six of them including β-catenin, DC-SIGN, C-MYC, EGFR, CXCL13 and PIM2 have been reported overexpressed in gastric tissue from infected children and gastric cancer patients (73). The gene discussed is PIM2; the disease is gastric cancer.