ITGAM and infection: Analysis of brain leukocytes 1 mo p.i. showed infection with Lm 10403s but not Δhly Lm mutants triggered significant increases compared with uninfected mice of bone marrow-derived leukocytes in general, i.e. CD45hi cells, as well as CD3+ T-lymphocytes and CD11b+ myeloid cells (Figures 6A–C).