In terms of pre-diagnosis disease duration, no significant difference was found between patients with hypoalbuminemia (2.0 (0.3-5.0) months) and those without (3.0 (0.5-12) months), p=0.458. Sixty-two out of 105 (59.1%) patients had high ESR and 67 of 104 (64.4%) had high CRP. This evidence concerns the gene CRP and Hypoalbuminemia.