ZDHHC4 palmitoylates KAI1 and affects its localization, inhibiting angiogenesis618; GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of GBM stem cells619; palmitoylation of D2R by ZDDHC4 is important for cell surface expression of the receptor.620. The gene discussed is DRD2; the disease is glioblastoma.