Furthermore, the reduced accumulation of Foxp3+ Treg cells and F4/80+ macrophages, up-regulation of TNFa, IFNg, IL10, down-regulation of IL1, IL6, IL12, TGFb, and decreased release of superoxide, may explain the role of FMT in inhibiting intestinal inflammation and CRC progression. This evidence concerns the gene IFNG and colorectal carcinoma.