Hypothyroidism is associated with various hormonal biochemical and nervous system abnormalities, which can lead to hypoglycemia, such as reduced basal and stimulated growth hormone or cortisol levels, blunted hypothalamo‐pituitary‐adrenal response, reduced glucogenesis, impaired glycogenolysis, reduced glucagon secretion, and slowing of insulin clearance.6, 7, 8. The gene discussed is GH1; the disease is Hypoglycemia.