Measurement of perfusate biomarkers during EVLP could provide an objective measurement of organ suitability for transplantation, via stratification on the basis of inflammation or injury-associated proteins or gene signatures.28-30 The IL-1 pathway has been implicated in multiple lung pathologies, with data linking IL-1β level with both inflammatory and fibrotic diseases, such as acute lung injury31,32 and idiopathic pulmonary fibrosis.33,34. The gene discussed is IL1B; the disease is pulmonary fibrosis.