NLRP3 and myeloid sarcoma: This elucidates the therapeutic effect of PDLSC-derived secretome in MS, acting similarly to the conventional immunosuppressant drugs, such as interferon-beta (IFN-β), and suppressing the NALP3 inflammasome and the NFkβ signaling pathway via secreting cytokines such as IL-10 and TGF-β [123].