This elucidates the therapeutic effect of PDLSC-derived secretome in MS, acting similarly to the conventional immunosuppressant drugs, such as interferon-beta (IFN-β), and suppressing the NALP3 inflammasome and the NFkβ signaling pathway via secreting cytokines such as IL-10 and TGF-β [123]. The gene discussed is IFNB1; the disease is myeloid sarcoma.