CAV1 and cancer: Several studies have shown that, based on the reverse Warburg effect theory, the upregulation of TGF-β caused by Cav-1 deletion can induce fibroblasts to undergo aerobic glycolysis and produce lactic acid while promoting the transformation of fibroblasts to myofibroblasts, which exhibit more pronounced activity in oxygenated glycolysis and autophagy, providing energy material to neighboring cancer cells.