Increased tissue expression levels of KRT7 is reported to be associated with LN metastasis in gallbladder cancer, lung cancer and colorectal cancer patients [28, 31, 32], KRT17 in gastric cancer, esophageal carcinoma and papillary thyroid carcinoma [33-35], KRT6A in lung adenocarcinoma [36], KRT19 in adenocarcinoma of gallbladder [37], thoracic tumors [38]. This evidence concerns the gene KRT19 and differentiated thyroid carcinoma.