Sorcin exert its oncogenic effect by regulating key molecules such as VEGFs, MMPs, NF-κB, ERK1/ 2, CTSZ, Akt, STAT3, caspases involved in carcinogenesis and invasion of tumor cells and modulating signaling pathways including ERK, MAPK/ERK, and PI3K/Akt in various cancers. The gene discussed is STAT3; the disease is neoplasm.