PDX1 and neoplasm: These included: (a) KPC PDAC tumor cell lines (KPC1, KPC2) derived from PDAC tumors in Pdx1-Cre; KrasLSL-G12D/wt;Trp53R172H/wt genetically engineered mouse models (GEMMs)31 and (b) KP LUAD cell lines (KP1, KP2) derived from lung tumors in KrasLSL-G12D/wt;Trp53flox/flox GEMMs administered an adenovirus expressing Cre-recombinase intratracheally32.