Cluster 6 mainly (but also clusters 7 and 10) could be defined by genes related to mesenchymal features and plasticity through EMT such as FOXC133, TIMP334, ETV135, and HGF and corresponded to the bridge population seen at the interface between noradrenergic tumor cells and normal Schwann cells in Fig. 6A (Fig. 6C, Supplementary Fig. 5D and Supplementary Data 1). This evidence concerns the gene HGF and neoplasm.