The IR of NHL was 10.5 (95% CI 1.5 to 74.3) per 100 000 person-years for patients not treated with thiopurines or anti-TNF-α therapy (SIR 0.9; 95% CI 0.6 to 1.3) (table 3). The gene discussed is TNF; the disease is non-Hodgkin lymphoma.