When gender differences in the genetic structure of depression were investigated, five genetic markers of increased risk of depression in women were obtained by qualitative analysis, three of which were rs201432982 in PDE4A, rs62640397, and rs79442975 in FDX1L, and the remaining two were rs820182 and rs820148 in MYO15B [32]. Here, PDE4A is linked to depressive symptom measurement.