Two heterozygous variants in PLA2G6 (NM_003560.4:c.2070_2072del (p.Val691del) and NM_003560.4: c.956C>T (p.Thr319Met)) were found in both siblings (Patient 1 and Patient 2) showing late onset parkinsonism. This evidence concerns the gene PLA2G6 and Parkinsonism.