Several genetic studies have identified many T1D-related polymorphisms for other TLRs, including polymorphisms in the TLR1 (rs4833095 and rs5743612) (40), TLR2 (rs3804100) (41), and TLR3 (rs5743313, rs5743315, rs3775291 and rs13126816) genes (42, 43). Here, TLR2 is linked to type 1 diabetes mellitus.