Our lab had identified a higher platelet mRNA expression of apoptotic chromatin coagulation inducing factor 1 (ACIN1) in lung cancer patients than in healthy controls (54), along with a three-platelet mRNA set—MAX, MTURN, and HLA-B—which was significantly upregulated in lung cancer patients processing a dramatically high diagnostic efficiency in female patients; the area under the curve (AUC) was 0.825 (51). Here, HLA-B is linked to lung cancer.