TNNI3 and atrial fibrillation: A meta-analysis of 51 studies with 7,675 HCM individuals found that 18% of HCM patients with MYBPC3 variants, 24% of MYH7, 33% of TNNT2, 30% of TNNI3, and 17% of genotype-negative (no pathogenic variants in sarcomere genes) patients showed supraventricular tachycardia, such as AF.