The MMRGs had few single nucleotide polymorphisms (SNPs) in patients in the TCGA-LAML cohorts, only three genes (SUCLA2, SURF1, and POLG) with somatic mutations among 31 MMRGs in three AML patiens (Figure 2A, Figure S2A), mainly missense mutation. Here, SURF1 is linked to acute myeloid leukemia.