The mutation profile of the 31 MMRGs in AML samples was analyzed to evaluate the mutation characteristic of the 31 MMRGs (BCS1L, COX10, COX15, DGUOK, ECHS1, ETHE1, FBXL4, LIAS, MPV17, NDUFA1, NDUFA13, NDUFAF5, NDUFS1, NDUFS2, NDUFS4, NDUFS7, NDUFV1, NFU1, POLG, POLG2, SDHA, SDHD, SLC25A4, SUCLA2, SUCLG1, SURF1, TACO1, TIMM8A, TMEM70, TRIT1, TTC19). Here, BCS1L is linked to acute myeloid leukemia.