The mutation profile of the 31 MMRGs in AML samples was analyzed to evaluate the mutation characteristic of the 31 MMRGs (BCS1L, COX10, COX15, DGUOK, ECHS1, ETHE1, FBXL4, LIAS, MPV17, NDUFA1, NDUFA13, NDUFAF5, NDUFS1, NDUFS2, NDUFS4, NDUFS7, NDUFV1, NFU1, POLG, POLG2, SDHA, SDHD, SLC25A4, SUCLA2, SUCLG1, SURF1, TACO1, TIMM8A, TMEM70, TRIT1, TTC19). This evidence concerns the gene NDUFA13 and acute myeloid leukemia.