MiR-195-5p, functioning as an anticancer agent, could inhibit M2-like TAM polarization in colorectal cancer (CRC) by regulating NOTCH2-mediated tumor cell epithelial-mesenchymal transition (EMT) and suppressing GATA3-mediated IL-4 secretion in CRC cells (93). The gene discussed is IL4; the disease is colorectal carcinoma.