PCBP1 and ovarian neoplasm: Recently, we found that another nucleic acid-binding protein, PCBP1 exhibits a role in the suppression of basal level autophagy in ovary tumor cells under normal culture situations [20], collectively confirming the existence of basal autophagy of cells and its instinct balance regulation by functionally opposite factors in cells to sustain the cell homeostasis and prevent cells from over self-eating or overgrowth for the appropriate organism function.