According to Hofmann et al. injected CD34+ cells may effectively accumulate in the area of ischemia and improve cardiac regeneration, While a significant portion of the injected-MNCs cramped in the spleen, liver, and the infarcted myocardium’s center, providing another proof of the superiority of CD34+ cells over MNCs (Hofmann et al., 2005). The gene discussed is CD34; the disease is ischemia.