CST1 and chronic rhinosinusitis with nasal polyps: Interestingly, a study involving proteomic analysis of the nasal mucus exosome in patients with CRSwNP has indicated that the unique bioimprints of cystatin-SN, peroxidase-5, and glycoprotein VI in the exosomes of CRSwNP nasal mucus could facilitate accurate prediction of the occurrence of this disease (60).