LINC00978 depletion in neutrophils, but not in intestinal epithelial cells (IECs), could lead to a decline of monocytes, neutrophils and eosinophils, and increase tumour‐infiltrating PMN myeloid‐derived suppressor cells (PMN‐MDSC) to promote the cancer development.86 This evidence concerns the gene MIR4435-2HG and neoplasm.