Elevated IL‐4 and miR‐324‐5p levels in tumour microenvironment caused a decreased expression level of CUEDC2 in tumour‐associated macrophages, which resulted in excessive levels of proinflammatory cytokines, such as TNF‐α and IL‐6, and linked with both colitis and colon carcinogenesis.83 This evidence concerns the gene CUEDC2 and neoplasm.