TRPV2 and esophageal squamous cell carcinoma: Nabissi et al. showed that TRPV2 induces and activates autophagy to promote tumor progression [35], whereas Li et al. found that TRPV2 promotes esophageal squamous cell carcinoma by activating the HSP70/27 and PI3K/Akt/mTOR pathways [26].