KRAS and neoplasm: The Gene Set Enrichment Analysis (GSEA) of hallmark pathways showed that KRAS signaling pathway [24], angiogenesis [25], G2M checkpoint [26], p53 pathway [27], and epithelial mesenchymal transition (EMT) [28], all of which play important roles in tumor progression, were significantly changed in myeloid-like tumor cells (Fig. 1g).