PITX2 and glaucoma: For instance, they found that genes implicated in glaucoma and anterior segment dysgenesis (PAX6 (paired box Pax-6), PITX2 (paired like homeodomain 2), FOXC1, CYP1B1, LTBP2 (latent transforming growth factor beta binding protein 2), FOXE3 (forkhead box E3), PITX3 (paired-like homeodomain transcription factor 3), B3GLCT (beta 3-glucosyltransferase), COL4A1 (collagen alpha-1(IV)), PXDN (peroxidasin), and CPAMD8 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8)) continued to be highly expressed in adult anterior segment cell types.