ANGPT1 and primary congenital glaucoma: Thomson et al. utilized scRNA-seq to demonstrate that loss-of-function mutations in angiopoietin (ANGPT1)-TEK (tunica interna endothelial cell kinase) or SVEP1 (sushi, von Willebrand factor type A, EGF, and pentraxin domain containing 1) is crucial to primary congenital glaucoma (PGC) development in murine models [77].