Moreover, the prognostic value of GPx2 expression in GC was investigated (Table 1), and the results showed that GPx2 overexpression was significantly correlated with N stage (P = 0.006) and KI67 expression (P = 0.029), while GPx2 expression was not significantly associated with age, sex, Lauren type, tumor size, T stage, M stage, TNM stage, CEA level or CA 199 level. This evidence concerns the gene MKI67 and neoplasm.