ADGRB1 and Parkinson disease: Adhesion G protein-coupled receptor B1 (ADGRB1 or brain-specific angiogenesis inhibitor 1, BAI1) regulates synaptic plasticity in learning and memory processes in the hippocampus.563 ADGRB1 is a post-synaptic receptor controlling excitatory synapse development.564,565 Forced ADGRB1 attenuates toxin-induced neuronal cell death.566 ADGRB1 is associated with dopaminergic neuronal loss in Parkinson’s disease.566