Next, we transfected IGF2BP1-overexpression plasmids into LINC02428-overexpression Huh7 and Hep3B cells and showed that IGF2BP1 overexpression reversed the LINC02428-induced decrease in HCC cell proliferation (Fig. 7A, C, D and S7A, C, D), migration, and invasion in vitro (Fig. 7G and S7G, I, J). The gene discussed is IGF2BP1; the disease is hepatocellular carcinoma.