CRP and heart failure: Additionally, overhydration in PD patients may contribute to uremic myocardiopathy, including heart failure and myocardial damage, as manifested by the stenosis or even occlusion of coronary arteries and injury of cardiac cells that may lead to myocardial stunning; subsequently, inflammation occurs with the activation of inflammatory cells, such as neutrophils and lymphocytes, as well as the overexpression of inflammatory factors, including CRP and IL-6[37,38].