13 of the 21 family members were found to be highly expressed in HCC tumor samples, including S100A1, S100A2, S100A3, S100A4, S100A5, S100A6, S100A10, S100A11, S100A13, S10016, S100P, and S100Z (Figure 1A). The gene discussed is S100A2; the disease is neoplasm.