Infection provokes an immune response by keratinocytes viatherelease of endogenous AMPs to thwart bacterial invasion.10 However, AMP expression and release can alsobe induced by other cationic compounds, which might act to prime theimmune system before bacterial attack.11 Considering that CD4-PP is a synthetic cationic AMP derived fromendogenous LL-37, we investigated whether CD4-PP could induce endogenousAMP production. The gene discussed is CD4; the disease is infection.