SCD and cancer: Recently, stearoyl CoA desaturase 1 (SCD1) (Fig. 4), an enzyme that catalyzes the rate-limiting step in monounsaturated fatty-acid synthesis, has been associated with ferroptosis resistance in a number of cancers and correlated with a worse prognosis (Liu et al., 2022b; Luis et al., 2021; Tesfay et al., 2019; Ye et al., 2021).