In addition, ADH-1-modified liposomes (A-LP) have been successfully constructed with the aim of enhancing chemotherapy efficacy and preventing metastasis and was tested using a PTX-resistant breast cancer cell line, MCF7 PTX-R, which was established into a tumour model using subcutaneous inoculation into the right flanks of female BALB/c nude mice. This evidence concerns the gene ADH1A and neoplasm.