Riby et al. demonstrated that 3,3‐diindolylmethane (50 μM) exhibited anti‐cancer activity by decreasing the expression of hypoxia‐responsive factors such as furin, and glucose transporter‐1, VEGF, enolase‐1, and phosphofructokinase in hypoxic specific MDA‐MB‐231 cells.141. This evidence concerns the gene VEGFA and cancer.