ERVW-1 and infection: IgG binding to whole RhCMV virions and key envelope glycoproteins, glycoprotein B (gB) and the pentameric complex (PC), shared similar kinetics, with detectable responses by 2 weeks post infection in most animals, with a sharp increase in antibody titers between 2–4 weeks post infection followed by a plateau or a more gradual increase in antibody levels throughout the remainder of the pregnancy (Figure 2B–E).