HMGA2 and lipoma: In contrast to WD-/DD-LPS, the genetic basis of some lipomas is attributed to translocations of HMGA2 (High Mobility Group AT-Hook 2) gene to various partners (LPP, CXCR7, EBF, LHFP, and NFIB).37, -39 HMGA2 acts as a transcriptional regulating factor and rearrangements result in deregulated activity.