EIF4EBP1 and fatty liver disease: Compared with untreated Ufbp1Δ/Δhep mice, the liver samples from rapamycin administered Ufbp1Δ/Δhep mice exhibited attenuated hepatic steatosis, as well as decreased cytoplasmic vacuolation, inflammatory cell infiltration, and phosphorylation levels of mTOR, p70S6, 4EBP-1, and GβL (Fig. 8D and F).