A study of 71 low-grade glioma patients of mixed IDH mutation status reported similar findings for PsP in terms of time of onset and duration, correlation with RT, and smaller size on MRI than TP.9 Several studies have reported PsP is associated with improved OS relative to TP in cohorts of mixed IDH status,11,14,18,19 and we observed this in our cohort of exclusively IDH mutant patients. Here, IDH2 is linked to central nervous system cancer.