While Il4r and Igf1 mRNA was expressed in Cd68/Aif1-positive tumour-associated microglia throughout drug-treated PDOX (Fig. 7c,d), Il4 expression co-localised with Gfap/S100b-expressing astrocytes exclusive to the interface region of drug-treated PDOX. The gene discussed is GFAP; the disease is neoplasm.