Altogether, 16 DKD-associated DEIRGs were identified including 3 common upregulated DEIRGs (CCL19, IL7R, and TRBC1), 9 common downregulated DEIRGs (GHR, FGF1, FYN, VEGFA, F2R, TGFBR3, PTGDS, FGF9, and SEMA5A), and 4 changed genes (Fig. 1). Here, SEMA5A is linked to diabetic kidney disease.