Higher UD16 (UDP-glucuronosyltransferase 1-6) worsened four LV CMR traits and increased the risk of DCM (OR, 1.62; 95% CI, 1.46 to 1.80) and CHD (OR, 1.06; 95% CI, 1.04 to 1.08). The gene discussed is UGT1A1; the disease is familial dilated cardiomyopathy.