By searching LncRNA Symbol with MALAT1 in the LncRNADisease v2.0 database (http://www.rnanut.net/lncrnadisease/index.php/home/search), we noticed that, except for cancers, MALAT1 also highly correlated with several VC-related diseases such as liver cirrhosis (Score = 0.9933), calcific aortic valve disease (Score = 0.9820), diabetic nephropathies (DN) (Score = 0.9630) and DM (Score = 0.9053); therefore, we speculate that MALAT1 may has a role in the pathogenesis of VC. Here, MALAT1 is linked to liver dysplastic nodule.