As shown in Figures 7(a)–7(e) and Table 4, decreased expression of EPAS1 in AML was significantly associated with WBC count (×109/L) (OR = 0.42 for >20 vs. <=20, P = 0.009), PB blasts (%) (OR = 0.46 for >70 vs. <=70, P = 0.019), BM blasts (%) (OR = 0.31 for >20 vs. <=20, P < 0.001), FLT3 mutation (OR = 0.41 for positive vs. negative, P = 0.017), and NPM1 mutation (OR = 0.20 for positive vs. negative, P < 0.001). The gene discussed is NPM1; the disease is acute myeloid leukemia.