After adjusting for age, sex, BMI, hypertension, diabetes, hyperuricemia, TG, TC, WBC, HGB, alcohol use, and smoke status, the baseline ApoB increase was still correlated with the occurrence of CKD (HR, 1.61; 95% CI: 1.02-2.54) (P = 0.042) (Table 4). The gene discussed is APOB; the disease is diabetes mellitus.