When adjusted for sex, age, BMI, hypertension, diabetes, hyperuricemia, TG, TC, WBC, HGB, alcohol use, and smoke status, ApoB at baseline remained significantly correlated with the CKD occurrence (HR, 1.76; 95% CI: 1.00-3.07) (P = 0.048) (Table 5). This evidence concerns the gene APOB and chronic kidney disease.