The multivariable logistic regression analysis showed that having a weight loss of ≥3% was negatively associated with increased HbA1c (adjusted odds ratio [aOR]=0.698, 95%CI: 0.522-0.933, p=0.015) and increased triglycerides (aOR=0.675, 0.520-0.876, p=0.003) after adjusting for age, sex, baseline BMI, education level, residence place, marital status, living relationships, household income, smoking status, alcohol drinking, duration of diabetes, antihypertensive medication use, oral hypoglycaemic drugs use, insulin use, and presence of CV comorbidities. This evidence concerns the gene INS and diabetes mellitus.