Among these, rs74637005 is located in the exonic region of NFU1, a gene previously shown to be associated with both calcium levels (Sakaue et al., 2021) and elevation in metabolic biomarkers (Martin et al., 2021) and rs17438465 is located between EVX1 and HIBADH, genes that have been associated with nephrolithiasis and cardiovascular disease (Howles et al., 2019; Kichaev et al., 2019). This evidence concerns the gene EVX1 and cardiovascular disorder.